January 6, 2009
| Bio-IT World

Top Headlines

Building Integrative Biology at Boehringer Ingelheim
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Bio-IT World |  Boehringer Ingelheim (BI), the German family-owned biopharmaceutical conglomerate, is making a (modest) bet on integrative biology at its Ridgefield, Conn., facility. Leading the new effort as VP of biotherapeutics and integrative biology is David de Graaf, who until last summer was Pfizer’s director of systems biology at the Research Technology Center (RTC).

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Coming Event: The 2009 Bio-IT World Expo
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Bio-IT World | The 2009 Bio-IT World Conference & Expo takes place April 27-29 in Boston. Full details of the program are available, but below are some of the editors’ highlights.

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Researchers Create Molecular Manual of Disease Networks
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Washington Post | An international research team has catalogued changes to tissues associated with different diseases.

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MORE NEWS BELOW

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Sanger Institute, MGH Target Personalized Cancer Medicine
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The Times | The UK's Wellcome Trust Sanger Institute and Mass General Hospital have launched a five-year study of "personalized cancer medicine" to “mix and match” tumours with drugs to develop personalised therapies for patients.

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Obama's New Respect for Science
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New York Times | With appointments of Steven Chu, John Holdren, and advisors including Harold Varmus and Eric Lander, the incoming Obama administration is signaling a new respect for science and potential initiatives in cancer research, stem cell biology and genomic medicine.

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Modeling & Simulation Still Need a Push
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Bio-IT World | To a considerable extent, the acceptance of modeling and simulation (M&S) approaches (beyond traditional PD/PK) inside biopharma remains stuck at a low level and something is needed to get it unstuck—especially among senior management.

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White Papers & Special Reports

Coupa white paper 92
10 Secrets to Recession-Proof Your Business
Sponsored by Coupa


Read this white paper to discover 10 strategies smart companies deploy to recession-proof their business.
Leaders generally face hard choices on how to mange a company during an economic downturn and
behave in one of three ways:
1) “The ostrich” - Preserve the status quo/hope for the best
2) “The bull in the china shop” - Blindly cut expenses across the board
3) “The fox” - Use the downturn to make your business more effective and position it for future growth

Learn how to behave “like a fox” and use a recession as a means to pounce on emerging trends.

SGI BriefingON image
High-Performance Computing in Life Science & Education
Sponsored by SGI and Intel
The varied collection of Bio-IT World articles and insights assembled in this BriefingON examine key trends in HPC infrastructure and how researchers are putting their best computational resources to use. Provided here are stories and lessons around the effective use of high performance computing in life science. Download the BriefingON.
Waters white paper image
Software Helps Doping Control Lab Streamline Results Management
Sponsored by Waters
The Karolinska University Hospital’s Doping Control Lab tests thousands of samples annually for stimulants, diuretics, and other masking agents. Increased regulatory pressure and new technologies increased the number of samples analyzed creating data management challenges. Waters® NuGenesis® Scientific Data Management System and TargetLynx™ Application Manager software were used to reduce the time required to calculate, review and search results.


Expert Comment

Build vs. Buy: Considerations for EDC Investment

By Ross Rothmeier
Covance Inc.

Nov. 17, 2008 | Companies looking to implement an electronic data capture (EDC) system have a wealth of choices. The ‘build versus buy’ scenario has been a major point of contention since the EDC industry emerged over 15 years ago. The question is still relevant today as pharmaceutical and biotechnology companies continue to look for opportunities to cut costs and maximize process efficiencies for conducting clinical trials. The question of whether to acquire EDC technology from a vendor or build it using internal capabilities is often at the forefront of long-term strategic decision-making. Read more. 

Bio-IT World invites contributed Expert Commentaries. Contact Kevin Davies with proposals.

Life Science Webcasts & Podcasts

Medidata Solutions

Rising Clinical Trial Delays and Costs - Addressing the Cause, Not the Symptoms 

medidata podcastProtocol complexity is taking a toll on clinical study speed and efficiency: increasingly complicated and ambitious protocols are not only burdening sites and study volunteers but are also prolonging trials and increasing expenses. In response, sponsors have turned to global study placement, restructured site relationships and new site management practices, but the problem remains.

This podcast will discuss:

  • Why these responses address only the symptoms, not the underlying cause, of rising clinical trial delays and costs.
  • Results of a recent joint Tufts University / Medidata Solutions study.
  • New metrics benchmarking protocol design trends.
  • Systematic protocol design improvements and why they are essential to clinical trial performance excellence.

Speakers: Ken Getz, Senior Research Fellow at the Tufts Center for the Study of Drug Development, and Ed Seguine, General Manager, Trial Planning Solutions at Medidata.

Download Now 



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